A Brief History of Stem Cell Research
Stem cell research is still ongoing since we still haven’t tapped its full potential yet. We already know some information about them, especially when it comes to medical treatments. However, despite the fact that it is still an ongoing study from the stem cell researcher, it is still remarkable if we look back to where it all began.
Stem Cell Research Timeline
1868- This is where the term “stem cell” was first coined, where the German Biologist by the name of Ernst Haeckel used it to describe how a fertilized egg (with the use of a sperm) becomes a living being.
1886- The term “stem cell” was used by William Sedgwick to describe the different parts of a plant that has the ability to grow and regenerate.
1909- This is the year where the blood cell was deemed to have come from what is known as the “ancestor cell”, which is later coined as the “stem cell” which has the ability to turn into specialized cells.
1953- The same characteristic was also documented by a Maine scientist that goes by the name of Leroy Stevens. He found out that some mice that had large tumors in their scrotums contain different types of differentiated and undifferentiated cells. He concluded that there are indeed cells that can turn into specialized cells, even if it means it would turn to eventual cancer cells.
1957- This is where the physician, E. Donnall Thomas, conducted the first-ever bone marrow transplantation procedure.
1963- This is the time where the blood stem cells were first discovered. It was found by two Canadian scientists, James Till and Ernest McCulloch. They observed the bone marrow of mice and it turns out that stem cells come from this particular region of the mice’s bodies.
1968- This is the time where Robert A. Good, an attending physician from the University of Minnesota, performed the first-ever successful bone marrow transplant that saved a boy’s life.
1981- Thanks to two scientists, Martin Evans and Gail Martin, we now know what embryonic stem cells are as they are first derived from the embryos of certain mice.
1986- Andrew Lassar and Harold Weintraub, both scientists from Seattle, Washington, has found out that adult stem cells are able to regenerate certain tissues in the body.
1997- It was in this year that both Dominique Bonnet and John Dick found that Leukemia can actually stem from our own blood cells.
1998- This is the time where the first batch of embryonic stem cells was documented and it was also at this time where the said cells have the property of pluripotency as well.
2002- The first documented use of gene and cell-based therapy in the treatment of various immunodeficiency conditions.
2005- The first ever documented conversion of embryonic stem cells transforming into blood stem cells in mice.
2009- This is the time where the iPS that were created in the laboratories are reported to be safe for use than other previous methods done before.